RaPaed-AIDA-TB is designed to study and further new diagnostic tools and testing strategies for children that would solve the challenge of obtaining samples easily from children and diagnosing TB in resource constrained settings.

The core of the project is a large diagnostic validation study, to be conducted in four centres in Africa and one in India. Eight new diagnostic test candidates will be conducted on all children in the study, and their performance compared to the reference standard used in child diagnostic validation studies.

The project brings together experienced academic medical study centres and a clinical trial unit at LMU, with academic test developers and major industry partners. Tests are established with promising platforms that will enable testing at point-of-care or in district hospital settings with acceptable referral timelines.

This project also supports the building of capacity to diagnose TB in children in African doctors and include further training of African researchers, in order to strengthen African health structures and research.