The unique setup of RaPaed-AIDA-TB allows the evaluation of multiple new test candidates and testing approaches:
Testing Strategies
Pathogen detection · Evaluation of the Xpert MTBRIF Ultra® cartridges on different specimen types · Lipoarabinomannan (LAM) detection in different specimen
Host immune response · Assessment of the T cell specific immune response: “T cell activation marker TB"
Host biomarker signatures · Protein based · RNA signatures
Furthermore, the project will contribute significantly to the establishment of a biorepository to facilitate future new test evaluation on stored paediatric samples.
